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Chemo- and Diastereoselective Hydrosilylation of Amorphadiene toward the Synthesis of Artemisinin
[Image: see text] A formal synthesis of artemisinin starting from amorphadiene is described. This new route relies on the development of a catalytic chemo- and diastereoselective hydrosilylation. The practicability of this method is demonstrated by converting amorphadiene to dihydroartemisinic aldeh...
Autores principales: | Schwertz, Geoffrey, Zanetti, Andrea, de Oliveira, Marllon Nascimento, Fernandez, Mario Andrés Gomez, Amara, Zacharias, Cossy, Janine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418106/ https://www.ncbi.nlm.nih.gov/pubmed/32643937 http://dx.doi.org/10.1021/acs.joc.0c00617 |
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