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Neurocognitive impacts of arbovirus infections
Arthropod-borne viruses or arbovirus, are most commonly associated with acute infections, resulting on various symptoms ranging from mild fever to more severe disorders such as hemorrhagic fever. Moreover, some arboviral infections can be associated with important neuroinflammation that can trigger...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418199/ https://www.ncbi.nlm.nih.gov/pubmed/32778106 http://dx.doi.org/10.1186/s12974-020-01904-3 |
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author | Clé, Marion Eldin, Patrick Briant, Laurence Lannuzel, Annie Simonin, Yannick Van de Perre, Philippe Cabié, André Salinas, Sara |
author_facet | Clé, Marion Eldin, Patrick Briant, Laurence Lannuzel, Annie Simonin, Yannick Van de Perre, Philippe Cabié, André Salinas, Sara |
author_sort | Clé, Marion |
collection | PubMed |
description | Arthropod-borne viruses or arbovirus, are most commonly associated with acute infections, resulting on various symptoms ranging from mild fever to more severe disorders such as hemorrhagic fever. Moreover, some arboviral infections can be associated with important neuroinflammation that can trigger neurological disorders including encephalitis, paralysis, ophthalmological impairments, or developmental defects, which in some cases, can lead to long-term defects of the central nervous system (CNS). This is well illustrated in Zika virus-associated congenital brain malformations but also in West Nile virus-induced synaptic dysfunctions that can last well beyond infection and lead to cognitive deficits. Here, we summarize clinical and mechanistic data reporting on cognitive disturbances triggered by arboviral infections, which may highlight growing public health issues spanning the five continents. |
format | Online Article Text |
id | pubmed-7418199 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-74181992020-08-11 Neurocognitive impacts of arbovirus infections Clé, Marion Eldin, Patrick Briant, Laurence Lannuzel, Annie Simonin, Yannick Van de Perre, Philippe Cabié, André Salinas, Sara J Neuroinflammation Review Arthropod-borne viruses or arbovirus, are most commonly associated with acute infections, resulting on various symptoms ranging from mild fever to more severe disorders such as hemorrhagic fever. Moreover, some arboviral infections can be associated with important neuroinflammation that can trigger neurological disorders including encephalitis, paralysis, ophthalmological impairments, or developmental defects, which in some cases, can lead to long-term defects of the central nervous system (CNS). This is well illustrated in Zika virus-associated congenital brain malformations but also in West Nile virus-induced synaptic dysfunctions that can last well beyond infection and lead to cognitive deficits. Here, we summarize clinical and mechanistic data reporting on cognitive disturbances triggered by arboviral infections, which may highlight growing public health issues spanning the five continents. BioMed Central 2020-08-10 /pmc/articles/PMC7418199/ /pubmed/32778106 http://dx.doi.org/10.1186/s12974-020-01904-3 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Review Clé, Marion Eldin, Patrick Briant, Laurence Lannuzel, Annie Simonin, Yannick Van de Perre, Philippe Cabié, André Salinas, Sara Neurocognitive impacts of arbovirus infections |
title | Neurocognitive impacts of arbovirus infections |
title_full | Neurocognitive impacts of arbovirus infections |
title_fullStr | Neurocognitive impacts of arbovirus infections |
title_full_unstemmed | Neurocognitive impacts of arbovirus infections |
title_short | Neurocognitive impacts of arbovirus infections |
title_sort | neurocognitive impacts of arbovirus infections |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418199/ https://www.ncbi.nlm.nih.gov/pubmed/32778106 http://dx.doi.org/10.1186/s12974-020-01904-3 |
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