Screening of BRCA1/2 genes mutations and copy number variations in patients with high risk for hereditary breast and ovarian cancer syndrome (HBOC)

BACKGROUND: Hereditary breast and ovarian cancer (HBOC) is an autosomal dominant inherited cancer susceptibility disorder. Both BRCA1 and BRCA2 genes are considered as high penetrance genes of this syndrome. The identification of BRCA1/2 genetic alterations before cancer development, grant patients...

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Detalles Bibliográficos
Autores principales: El Ansari, Fatima Zahra, Jouali, Farah, Marchoudi, Nabila, Bennani, Mohcine Mechita, Ghailani, Naima Nourouti, Barakat, Amina, Fekkak, Jamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418307/
https://www.ncbi.nlm.nih.gov/pubmed/32778078
http://dx.doi.org/10.1186/s12885-020-07250-0

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