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Enterococcus faecium: from microbiological insights to practical recommendations for infection control and diagnostics

Early in its evolution, Enterococcus faecium acquired traits that allowed it to become a successful nosocomial pathogen. E. faecium inherent tenacity to build resistance to antibiotics and environmental stressors that allows the species to thrive in hospital environments. The continual wide use of a...

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Autores principales: Zhou, Xuewei, Willems, Rob J. L., Friedrich, Alexander W., Rossen, John W. A., Bathoorn, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418317/
https://www.ncbi.nlm.nih.gov/pubmed/32778149
http://dx.doi.org/10.1186/s13756-020-00770-1
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author Zhou, Xuewei
Willems, Rob J. L.
Friedrich, Alexander W.
Rossen, John W. A.
Bathoorn, Erik
author_facet Zhou, Xuewei
Willems, Rob J. L.
Friedrich, Alexander W.
Rossen, John W. A.
Bathoorn, Erik
author_sort Zhou, Xuewei
collection PubMed
description Early in its evolution, Enterococcus faecium acquired traits that allowed it to become a successful nosocomial pathogen. E. faecium inherent tenacity to build resistance to antibiotics and environmental stressors that allows the species to thrive in hospital environments. The continual wide use of antibiotics in medicine has been an important driver in the evolution of E. faecium becoming a highly proficient hospital pathogen. For successful prevention and reduction of nosocomial infections with vancomycin resistant E. faecium (VREfm), it is essential to focus on reducing VREfm carriage and spread. The aim of this review is to incorporate microbiological insights of E. faecium into practical infection control recommendations, to reduce the spread of hospital-acquired VREfm (carriage and infections). The spread of VREfm can be controlled by intensified cleaning procedures, antibiotic stewardship, rapid screening of VREfm carriage focused on high-risk populations, and identification of transmission routes through accurate detection and typing methods in outbreak situations. Further, for successful management of E. faecium, continual innovation in the fields of diagnostics, treatment, and eradication is necessary.
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spelling pubmed-74183172020-08-12 Enterococcus faecium: from microbiological insights to practical recommendations for infection control and diagnostics Zhou, Xuewei Willems, Rob J. L. Friedrich, Alexander W. Rossen, John W. A. Bathoorn, Erik Antimicrob Resist Infect Control Review Early in its evolution, Enterococcus faecium acquired traits that allowed it to become a successful nosocomial pathogen. E. faecium inherent tenacity to build resistance to antibiotics and environmental stressors that allows the species to thrive in hospital environments. The continual wide use of antibiotics in medicine has been an important driver in the evolution of E. faecium becoming a highly proficient hospital pathogen. For successful prevention and reduction of nosocomial infections with vancomycin resistant E. faecium (VREfm), it is essential to focus on reducing VREfm carriage and spread. The aim of this review is to incorporate microbiological insights of E. faecium into practical infection control recommendations, to reduce the spread of hospital-acquired VREfm (carriage and infections). The spread of VREfm can be controlled by intensified cleaning procedures, antibiotic stewardship, rapid screening of VREfm carriage focused on high-risk populations, and identification of transmission routes through accurate detection and typing methods in outbreak situations. Further, for successful management of E. faecium, continual innovation in the fields of diagnostics, treatment, and eradication is necessary. BioMed Central 2020-08-10 /pmc/articles/PMC7418317/ /pubmed/32778149 http://dx.doi.org/10.1186/s13756-020-00770-1 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Zhou, Xuewei
Willems, Rob J. L.
Friedrich, Alexander W.
Rossen, John W. A.
Bathoorn, Erik
Enterococcus faecium: from microbiological insights to practical recommendations for infection control and diagnostics
title Enterococcus faecium: from microbiological insights to practical recommendations for infection control and diagnostics
title_full Enterococcus faecium: from microbiological insights to practical recommendations for infection control and diagnostics
title_fullStr Enterococcus faecium: from microbiological insights to practical recommendations for infection control and diagnostics
title_full_unstemmed Enterococcus faecium: from microbiological insights to practical recommendations for infection control and diagnostics
title_short Enterococcus faecium: from microbiological insights to practical recommendations for infection control and diagnostics
title_sort enterococcus faecium: from microbiological insights to practical recommendations for infection control and diagnostics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418317/
https://www.ncbi.nlm.nih.gov/pubmed/32778149
http://dx.doi.org/10.1186/s13756-020-00770-1
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