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GM-CSF induces noninflammatory proliferation of microglia and disturbs electrical neuronal network rhythms in situ
BACKGROUND: The granulocyte-macrophage colony-stimulating factor (GM-CSF) (or CSF-2) is involved in myeloid cell growth and differentiation, and, possibly, a major mediator of inflammation in body tissues. The role of GM-CSF in the activation of microglia (CNS resident macrophages) and the consequen...
Autores principales: | Dikmen, Hasan Onur, Hemmerich, Marc, Lewen, Andrea, Hollnagel, Jan-Oliver, Chausse, Bruno, Kann, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418331/ https://www.ncbi.nlm.nih.gov/pubmed/32782006 http://dx.doi.org/10.1186/s12974-020-01903-4 |
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