Eflapegrastim, a Long‐Acting Granulocyte‐Colony Stimulating Factor for the Management of Chemotherapy‐Induced Neutropenia: Results of a Phase III Trial

BACKGROUND: Eflapegrastim, a novel, long‐acting recombinant human granulocyte‐colony stimulating factor (rhG‐CSF), consists of a rhG‐CSF analog conjugated to a human IgG4 Fc fragment via a short polyethylene glycol linker. Preclinical and phase I and II pharmacodynamic and pharmacokinetic data showe...

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Detalles Bibliográficos
Autores principales: Schwartzberg, Lee S., Bhat, Gajanan, Peguero, Julio, Agajanian, Richy, Bharadwaj, Jayaram S., Restrepo, Alvaro, Hlalah, Osama, Mehmi, Inderjit, Chawla, Shanta, Hasal, Steven J., Yang, Zane, Cobb, Patrick Wayne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Symptom Management and Supportive Care
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418343/
https://www.ncbi.nlm.nih.gov/pubmed/32476162
http://dx.doi.org/10.1634/theoncologist.2020-0105

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