Microglial burden, activation and dystrophy patterns in frontotemporal lobar degeneration

BACKGROUND: Microglial dysfunction is implicated in frontotemporal lobar degeneration (FTLD). Although studies have reported excessive microglial activation or senescence (dystrophy) in Alzheimer’s disease (AD), few have explored this in FTLD. We examined regional patterns of microglial burden, acti...

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Detalles Bibliográficos
Autores principales: Woollacott, Ione O. C., Toomey, Christina E., Strand, Catherine, Courtney, Robert, Benson, Bridget C., Rohrer, Jonathan D., Lashley, Tammaryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418403/
https://www.ncbi.nlm.nih.gov/pubmed/32778130
http://dx.doi.org/10.1186/s12974-020-01907-0

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