ContamLD: estimation of ancient nuclear DNA contamination using breakdown of linkage disequilibrium

We report a method called ContamLD for estimating autosomal ancient DNA (aDNA) contamination by measuring the breakdown of linkage disequilibrium in a sequenced individual due to the introduction of contaminant DNA. ContamLD leverages the idea that contaminants should have haplotypes uncorrelated to...

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Detalles Bibliográficos
Autores principales: Nakatsuka, Nathan, Harney, Éadaoin, Mallick, Swapan, Mah, Matthew, Patterson, Nick, Reich, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418405/
https://www.ncbi.nlm.nih.gov/pubmed/32778142
http://dx.doi.org/10.1186/s13059-020-02111-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418405/
https://www.ncbi.nlm.nih.gov/pubmed/32778142
http://dx.doi.org/10.1186/s13059-020-02111-2

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