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Memantine ameliorates motor impairments and pathologies in a mouse model of neuromyelitis optica spectrum disorders
BACKGROUND: Neuromyelitis optica spectrum disorders (NMOSD) are central nervous system (CNS) autoimmune inflammatory demyelinating diseases characterized by recurrent episodes of acute optic neuritis and transverse myelitis. Aquaporin-4 immunoglobulin G (AQP4-IgG) autoantibodies, which target the wa...
Autores principales: | Yick, Leung-Wah, Tang, Chi-Ho, Ma, Oscar Ka-Fai, Kwan, Jason Shing-Cheong, Chan, Koon-Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418436/ https://www.ncbi.nlm.nih.gov/pubmed/32782018 http://dx.doi.org/10.1186/s12974-020-01913-2 |
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