Cargando…

The effectiveness of afatinib in patients with lung adenocarcinoma harboring complex epidermal growth factor receptor mutation

BACKGROUND AND AIMS: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) are effective against classical EGFR mutations in lung cancer. However, their effectiveness and the prognosis of lung cancer patients with complex EGFR mutations are not well delineated. Therefore, we aimed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Shang-Gin, Yu, Chong-Jen, Yang, James Chih-Hsin, Shih, Jin-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Advances in Treatment of Lung Cancer Patients With Targetable Mutations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418472/ https://www.ncbi.nlm.nih.gov/pubmed/32843903 http://dx.doi.org/10.1177/1758835920946156

Ejemplares similares

Hypothesis generative head-to-head study comparing efficacy of afatinib and osimertinib based on immunological biomarkers in Japanese NSCLC patients with EGFR mutations (Heat on Beat study)
por: Morikawa, Kei, et al.
Publicado: (2020)

Systemic therapy in metastatic pancreatic adenocarcinoma: current practice and perspectives
por: Lellouche, Lisa, et al.
Publicado: (2021)

Lorlatinib in pretreated ALK- or ROS1-positive lung cancer and impact of TP53 co-mutations: results from the German early access program
por: Frost, Nikolaj, et al.
Publicado: (2021)

The relative importance of predictive factors for single first-generation EGFR-TKI use for more than 5 years in patients with advanced non-small cell lung cancer: Taiwan multicenter TIPS-5 study
por: Huang, Yen-Hsiang, et al.
Publicado: (2021)

EGFR/c-Met and mTOR signaling are predictors of survival in non-small cell lung cancer
por: Crees, Zachary D, et al.
Publicado: (2020)

Bayesian network meta-analysis of efficacy and safety of neoadjuvant therapy for non-small-cell lung cancer
por: Ren, Yijiu, et al.
Publicado: (2020)

Selpercatinib in RET fusion-positive non-small-cell lung cancer (SIREN): a retrospective analysis of patients treated through an access program
por: Illini, Oliver, et al.
Publicado: (2021)

Clinical Outcomes of Afatinib Versus Osimertinib in Patients With Non-Small Cell Lung Cancer With Uncommon EGFR Mutations: A Pooled Analysis
por: Wang, Chunsheng, et al.
Publicado: (2023)

Mitochondrial tRNA mutations in Chinese children with tic disorders
por: Jiang, Peifang, et al.
Publicado: (2020)

Identification of a frame shift mutation in the CCDC151 gene in a Han-Chinese family with Kartagener syndrome
por: Deng, Sheng, et al.
Publicado: (2020)

Reply to comments on: “Obesity associated with a novel mitochondrial tRNA(Cys) 5802A>G mutation in a Chinese family”
por: Wang, Jinling, et al.
Publicado: (2020)

Advances in the Treatment of Rare Epidermal Growth Factor Receptor Mutations in Advanced Nonsmall-Cell Lung Cancer
por: Yu, Limeng, et al.
Publicado: (2023)

Targeted Next-Generation Sequencing Reveals Exceptionally High Rates of Molecular Driver Mutations in Never-Smokers With Lung Adenocarcinoma
por: Mack, Philip C, et al.
Publicado: (2022)

Identification of an unknown frameshift variant of NOG in a Han Chinese family with proximal symphalangism
por: Yuan, Zhuang-Zhuang, et al.
Publicado: (2020)

The association between Interleukin-6 rs1800795/rs1800797 polymorphisms and risk of rotator cuff tear in a Chinese population
por: Li, Jin, et al.
Publicado: (2020)

Role of matrix metalloproteases 1/3 gene polymorphisms in patients with rotator cuff tear
por: Miao, Kaisong, et al.
Publicado: (2019)

Characterization of functionally deficient SIM2 variants found in patients with neurological phenotypes
por: Button, Emily L., et al.
Publicado: (2022)

Genetic variants and haplotypes in fibulin-5 (FBLN5) are associated with pseudoexfoliation glaucoma but not with pseudoexfoliation syndrome
por: Kapuganti, Ramani Shyam, et al.
Publicado: (2023)

Safety and Success of Repeat Lung Needle Biopsies in Patients with Epidermal Growth Factor Receptor‐Mutant Lung Cancer
por: Fintelmann, Florian J., et al.
Publicado: (2019)

Deep learning with test-time augmentation for radial endobronchial ultrasound image differentiation: a multicentre verification study
por: Yu, Kai-Lun, et al.
Publicado: (2023)

Hypoxia and the Tumor Microenvironment
por: Li, Yue, et al.
Publicado: (2021)

Silica-Coated Fe(3)O(4) Nanoparticles as a Bifunctional Agent for Magnetic Resonance Imaging and ZnII Fluorescent Sensing
por: Qiu, Lin, et al.
Publicado: (2021)

Tumor Targeting by Conditioned Medium Derived From Human Amniotic Membrane: New Insight in Breast Cancer Therapy
por: Jafari, Ameneh, et al.
Publicado: (2021)

Identification of a Signature Comprising 5 Soluble Carrier Family Genes to Predict the Recurrence of Papillary Thyroid Carcinoma
por: Han, Rui, et al.
Publicado: (2021)

Next Generation Sequencing Reveals Pathogenic and Actionable Genetic Alterations of Soft Tissue Sarcoma in Chinese Patients: A Single Center Experience
por: Jin, Gu, et al.
Publicado: (2021)

Differential clinicopathological features, treatments and outcomes in patients with Exon 19 deletion and Exon 21 L858R EGFR mutation-positive adenocarcinoma non-small-cell lung cancer
por: Batra, Ullas, et al.
Publicado: (2023)

Lower starting dose of afatinib for the treatment of metastatic lung adenocarcinoma harboring exon 21 and exon 19 mutations
por: Chen, Yi-Chieh, et al.
Publicado: (2021)

Afatinib treatment response in advanced lung adenocarcinomas harboring uncommon mutations
por: Li, Teng, et al.
Publicado: (2021)

POST-COVID-19 CHANGES MASKED A MALIGNANCY: INVASIVE MUCINOUS ADENOCARCINOMA
por: DAMANI, JALAL A, et al.
Publicado: (2022)

The mechanism of acquired resistance to irreversible EGFR tyrosine kinase inhibitor-afatinib in lung adenocarcinoma patients
por: Wu, Shang-Gin, et al.
Publicado: (2016)

Impact of High-Grade Patterns in Early-Stage Lung Adenocarcinoma: A Multicentric Analysis
por: Bertoglio, Pietro, et al.
Publicado: (2022)

Feasibility study of in vitro drug sensitivity assay of advanced non-small cell lung adenocarcinomas
por: Papp, Emoke, et al.
Publicado: (2020)

PRIMARY PULMONARY CAVITATING ADENOCARCINOMA IN A PATIENT PRESENTING WITH COVID-19 PNEUMONIA: A CASE REPORT
por: TIJANI, SULAIMAN, et al.
Publicado: (2022)

Mutation update for the ACTN2 gene
por: Ranta‐aho, Johanna, et al.
Publicado: (2022)

Tubulin Alpha-1b as a Potential Biomarker for Lung Adenocarcinoma Diagnosis and Prognosis
por: Pang, Xue-Li, et al.
Publicado: (2023)

441 Cutaneous findings in COVID-19 patients hospitalized at a large urban academic medical center
por: Chand, S., et al.
Publicado: (2021)

461 A review of cutaneous lymphoma outcomes during COVID-19 pandemic at Columbia University
por: Garcia-Saleem, T., et al.
Publicado: (2021)

433 Increased risk of hospital acquired sacral pressure injuries in COVID-19 patients
por: Narang, J., et al.
Publicado: (2021)

A RARE PRESENTATION OF PRIMARY LUNG ADENOCARCINOMA PRESENTING WITH PERICARDIAL EFFUSION AND TAMPONADE IN A COVID-19 POSITIVE PATIENT
por: FOLARANMI, OLUFUNMILAYO, et al.
Publicado: (2021)

The clinical efficacy of Afatinib 30 mg daily as starting dose may not be inferior to Afatinib 40 mg daily in patients with stage IV lung Adenocarcinoma harboring exon 19 or exon 21 mutations
por: Yang, Chih-Jen, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_9dr72vm0siqoop4c220576n9l3