Exploiting replicative stress in gynecological cancers as a therapeutic strategy

Elevated levels of replicative stress in gynecological cancers arising from uncontrolled oncogenic activation, loss of key tumor suppressors, and frequent defects in the DNA repair machinery are an intrinsic vulnerability for therapeutic exploitation. The presence of replication stress activates the...

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Detalles Bibliográficos
Autores principales: Ngoi, Natalie YL, Sundararajan, Vignesh, Tan, David SP
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418601/
https://www.ncbi.nlm.nih.gov/pubmed/32571890
http://dx.doi.org/10.1136/ijgc-2020-001277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418601/
https://www.ncbi.nlm.nih.gov/pubmed/32571890
http://dx.doi.org/10.1136/ijgc-2020-001277

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