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COVID-19 interventions in some European countries induced bifurcations stabilizing low death states against high death states: An eigenvalue analysis based on the order parameter concept of synergetics

Taking a dynamical systems perspective, COVID-19 infections are assumed to spread out in a human population via an instability. Conversely, government interventions to reduce the spread of the disease and the number of fatalities may induce a bifurcation that stabilizes a desirable state with low nu...

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Autor principal: Frank, T.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418651/
https://www.ncbi.nlm.nih.gov/pubmed/32834661
http://dx.doi.org/10.1016/j.chaos.2020.110194
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author Frank, T.D.
author_facet Frank, T.D.
author_sort Frank, T.D.
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description Taking a dynamical systems perspective, COVID-19 infections are assumed to spread out in a human population via an instability. Conversely, government interventions to reduce the spread of the disease and the number of fatalities may induce a bifurcation that stabilizes a desirable state with low numbers of COVID-19 cases and associated deaths. The key characteristic feature of an infection dynamical system in this context is the eigenvalue that determines the stability of the states under consideration and is known in synergetics as the order parameter eigenvalue. Using a SEIR-like infection disease model, the relevant order parameter and its eigenvalue are determined. A three stage methodology is proposed to track and estimate the eigenvalue through time. The method is applied to COVID-19 infection data reported from 20 European countries during the period of January 1, 2020 to June 15. It is shown that in 15 out of the 20 countries the eigenvalue switched its sign suggesting that during the reporting period an intervention bifurcation took place that stabilized the desirable low death state. It is shown that the eigenvalue analysis also allows for a ranking of countries by the degree of the stability of the infection-free state. For the investigated countries, Ireland was found to exhibit the most stable infection-free state. Finally, a six point classification scheme is suggested with groups 5 and 6 including countries that failed to stabilize the desirable infection-free low death state. In doing so, tools for assessing the effectiveness of government interventions are provided that are at the heart of bifurcation theory, in general, and synergetics, in particular.
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spelling pubmed-74186512020-08-12 COVID-19 interventions in some European countries induced bifurcations stabilizing low death states against high death states: An eigenvalue analysis based on the order parameter concept of synergetics Frank, T.D. Chaos Solitons Fractals Article Taking a dynamical systems perspective, COVID-19 infections are assumed to spread out in a human population via an instability. Conversely, government interventions to reduce the spread of the disease and the number of fatalities may induce a bifurcation that stabilizes a desirable state with low numbers of COVID-19 cases and associated deaths. The key characteristic feature of an infection dynamical system in this context is the eigenvalue that determines the stability of the states under consideration and is known in synergetics as the order parameter eigenvalue. Using a SEIR-like infection disease model, the relevant order parameter and its eigenvalue are determined. A three stage methodology is proposed to track and estimate the eigenvalue through time. The method is applied to COVID-19 infection data reported from 20 European countries during the period of January 1, 2020 to June 15. It is shown that in 15 out of the 20 countries the eigenvalue switched its sign suggesting that during the reporting period an intervention bifurcation took place that stabilized the desirable low death state. It is shown that the eigenvalue analysis also allows for a ranking of countries by the degree of the stability of the infection-free state. For the investigated countries, Ireland was found to exhibit the most stable infection-free state. Finally, a six point classification scheme is suggested with groups 5 and 6 including countries that failed to stabilize the desirable infection-free low death state. In doing so, tools for assessing the effectiveness of government interventions are provided that are at the heart of bifurcation theory, in general, and synergetics, in particular. Elsevier Ltd. 2020-11 2020-08-11 /pmc/articles/PMC7418651/ /pubmed/32834661 http://dx.doi.org/10.1016/j.chaos.2020.110194 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Frank, T.D.
COVID-19 interventions in some European countries induced bifurcations stabilizing low death states against high death states: An eigenvalue analysis based on the order parameter concept of synergetics
title COVID-19 interventions in some European countries induced bifurcations stabilizing low death states against high death states: An eigenvalue analysis based on the order parameter concept of synergetics
title_full COVID-19 interventions in some European countries induced bifurcations stabilizing low death states against high death states: An eigenvalue analysis based on the order parameter concept of synergetics
title_fullStr COVID-19 interventions in some European countries induced bifurcations stabilizing low death states against high death states: An eigenvalue analysis based on the order parameter concept of synergetics
title_full_unstemmed COVID-19 interventions in some European countries induced bifurcations stabilizing low death states against high death states: An eigenvalue analysis based on the order parameter concept of synergetics
title_short COVID-19 interventions in some European countries induced bifurcations stabilizing low death states against high death states: An eigenvalue analysis based on the order parameter concept of synergetics
title_sort covid-19 interventions in some european countries induced bifurcations stabilizing low death states against high death states: an eigenvalue analysis based on the order parameter concept of synergetics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418651/
https://www.ncbi.nlm.nih.gov/pubmed/32834661
http://dx.doi.org/10.1016/j.chaos.2020.110194
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