Arsenic Metabolism in Mice Carrying a BORCS7/AS3MT Locus Humanized by Syntenic Replacement

BACKGROUND: Chronic exposure to inorganic arsenic (iAs) is a significant public health problem. Methylation of iAs by arsenic methyltransferase (AS3MT) controls iAs detoxification and modifies risks of iAs-induced diseases. Mechanisms underlying these diseases have been extensively studied using ani...

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Detalles Bibliográficos
Autores principales: Koller, Beverly H., Snouwaert, John N., Douillet, Christelle, Jania, Leigh A., El-Masri, Hisham, Thomas, David J., Stýblo, Miroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418654/
https://www.ncbi.nlm.nih.gov/pubmed/32779937
http://dx.doi.org/10.1289/EHP6943

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