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Effect of hypertonic saline on mucociliary clearance and clinical outcomes in chronic bronchitis

BACKGROUND: Mucus dehydration and impaired mucus clearance are common features of cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD). In CF, inhaled hypertonic saline (HS) improves lung function and produces sustained increases in mucociliary clearance (MCC). We hypothesised that...

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Detalles Bibliográficos
Autores principales: Bennett, William D., Henderson, Ashley G., Ceppe, Agathe, Zeman, Kirby L., Wu, Jihong, Gladman, Christine, Fuller, Fred, Gazda, Stephen, Button, Brian, Boucher, Richard C., Donaldson, Scott H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418818/
https://www.ncbi.nlm.nih.gov/pubmed/32802823
http://dx.doi.org/10.1183/23120541.00269-2020