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CD163(+) cytokine-producing cDC2 stimulate intratumoral type 1 T cell responses in HPV16-induced oropharyngeal cancer
BACKGROUND: Human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) is a distinct clinical entity with a much better prognosis after (chemo)radiotherapy than HPV-negative OPSCC, especially in patients with a concomitant intratumoral HPV-specific and type-1 cytokine-orient...
Autores principales: | Santegoets, Saskia J, Duurland, Chantal L, Jordanova, Ekaterina J, van Ham, Vanessa J, Ehsan, Ilina, Loof, Nikki M, Narang, Vipin, Dutertre, Charles A, Ginhoux, Florent, van Egmond, Sylvia L, J P Welters, Marij, van der Burg, Sjoerd H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418847/ https://www.ncbi.nlm.nih.gov/pubmed/32771994 http://dx.doi.org/10.1136/jitc-2020-001053 |
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