Discovery and validation of surface N-glycoproteins in MM cell lines and patient samples uncovers immunotherapy targets

BACKGROUND: Multiple myeloma (MM) is characterized by clonal expansion of malignant plasma cells in the bone marrow. While recent advances in treatment for MM have improved patient outcomes, the 5-year survival rate remains ~50%. A better understanding of the MM cell surface proteome could facilitat...

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Detalles Bibliográficos
Autores principales: Oldham, Robyn A A, Faber, Mary L, Keppel, Theodore R, Buchberger, Amanda R, Waas, Matthew, Hari, Parameswaran, Gundry, Rebekah L, Medin, Jeffrey A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418848/
https://www.ncbi.nlm.nih.gov/pubmed/32771993
http://dx.doi.org/10.1136/jitc-2020-000915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418848/
https://www.ncbi.nlm.nih.gov/pubmed/32771993
http://dx.doi.org/10.1136/jitc-2020-000915

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