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Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells
BACKGROUND: Current immune checkpoint blockade strategies have been successful in treating certain types of solid cancer. However, checkpoint blockade monotherapies have not been successful against most hematological malignancies including multiple myeloma and leukemia. There is an urgent need to id...
Autores principales: | Chen, Heyu, Chen, Yuanzhi, Deng, Mi, John, Samuel, Gui, Xun, Kansagra, Ankit, Chen, Weina, Kim, Jaehyup, Lewis, Cheryl, Wu, Guojin, Xie, Jingjing, Zhang, Lingbo, Huang, Ryan, Liu, Xiaoye, Arase, Hisashi, Huang, Yang, Yu, Hai, Luo, Wenxin, Xia, Ningshao, Zhang, Ningyan, An, Zhiqiang, Zhang, Cheng Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418854/ https://www.ncbi.nlm.nih.gov/pubmed/32771992 http://dx.doi.org/10.1136/jitc-2019-000515 |
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