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SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis

Human immunodeficiency virus infection is the most common risk factor for severe forms of tuberculosis (TB), regardless of CD4 T cell count. Using a well-characterized cynomolgus macaque model of human TB, we compared radiographic, immunologic and microbiologic characteristics of early (subclinical)...

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Detalles Bibliográficos
Autores principales:	Diedrich, Collin R., Rutledge, Tara, Maiello, Pauline, Baranowski, Tonilynn M., White, Alexander G., Borish, H. Jacob, Karell, Paul, Hopkins, Forrest, Brown, Jessica, Fortune, Sarah M., Flynn, JoAnne L., Ambrose, Zandrea, Lin, Philana Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419014/ https://www.ncbi.nlm.nih.gov/pubmed/32730321 http://dx.doi.org/10.1371/journal.ppat.1008413

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