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Mechanism underlying the development of myeloproliferative neoplasms through mutant calreticulin

Deregulation of cytokine signaling is frequently associated with various pathological conditions, including malignancies. In patients with myeloproliferative neoplasms (MPNs), recurrent somatic mutations in the calreticulin (CALR) gene, which encodes a molecular chaperone that resides in the endopla...

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Detalles Bibliográficos
Autores principales:	Edahiro, Yoko, Araki, Marito, Komatsu, Norio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419020/ https://www.ncbi.nlm.nih.gov/pubmed/32462673 http://dx.doi.org/10.1111/cas.14503

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