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Advances in oligonucleotide drug delivery
Oligonucleotides can be used to modulate gene expression via a range of processes including RNAi, target degradation by RNase H-mediated cleavage, splicing modulation, non-coding RNA inhibition, gene activation and programmed gene editing. As such, these molecules have potential therapeutic applicat...
Autores principales: | Roberts, Thomas C., Langer, Robert, Wood, Matthew J. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419031/ https://www.ncbi.nlm.nih.gov/pubmed/32782413 http://dx.doi.org/10.1038/s41573-020-0075-7 |
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