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Intracranial hemorrhage in a young COVID-19 patient
COVID-19 patients are increasingly understood to develop multisystem manifestations, including neurologic involvement. We report the case of a 42-year old COVID-19 positive patient with a fatal intracerebral hemorrhage (ICH). The patient presented with fever and dyspnea, requiring intubation due to...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier B.V.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419270/ https://www.ncbi.nlm.nih.gov/pubmed/32837915 http://dx.doi.org/10.1016/j.inat.2020.100878 |
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author | Khattar, Nicolas K. Sharma, Mayur McCallum, Abigail P. Oxford, Brent G. Zeb, Hassan Suliman, Sally A. Sieg, Emily P. Mocco, J Neimat, Joseph S. Zemmar, Ajmal |
author_facet | Khattar, Nicolas K. Sharma, Mayur McCallum, Abigail P. Oxford, Brent G. Zeb, Hassan Suliman, Sally A. Sieg, Emily P. Mocco, J Neimat, Joseph S. Zemmar, Ajmal |
author_sort | Khattar, Nicolas K. |
collection | PubMed |
description | COVID-19 patients are increasingly understood to develop multisystem manifestations, including neurologic involvement. We report the case of a 42-year old COVID-19 positive patient with a fatal intracerebral hemorrhage (ICH). The patient presented with fever and dyspnea, requiring intubation due to medical complications. After prolonged sedation and anticoagulation, the patient suddenly developed bilaterally fixed and dilated pupils, caused by a right-sided intracranial hemorrhage with uncal herniation. The course of this case illustrates the delicate balance between hypercoagulability and coagulation factor depletion; especially in the intubated and sedated patient, in whom regular neurological assessments are impeded. As we expand our understanding of the neurological ramifications of COVID-19, clinicians need to be increasingly aware of the precarious coagulation balance. |
format | Online Article Text |
id | pubmed-7419270 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Authors. Published by Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-74192702020-08-12 Intracranial hemorrhage in a young COVID-19 patient Khattar, Nicolas K. Sharma, Mayur McCallum, Abigail P. Oxford, Brent G. Zeb, Hassan Suliman, Sally A. Sieg, Emily P. Mocco, J Neimat, Joseph S. Zemmar, Ajmal Interdiscip Neurosurg Case Reports & Case Series COVID-19 patients are increasingly understood to develop multisystem manifestations, including neurologic involvement. We report the case of a 42-year old COVID-19 positive patient with a fatal intracerebral hemorrhage (ICH). The patient presented with fever and dyspnea, requiring intubation due to medical complications. After prolonged sedation and anticoagulation, the patient suddenly developed bilaterally fixed and dilated pupils, caused by a right-sided intracranial hemorrhage with uncal herniation. The course of this case illustrates the delicate balance between hypercoagulability and coagulation factor depletion; especially in the intubated and sedated patient, in whom regular neurological assessments are impeded. As we expand our understanding of the neurological ramifications of COVID-19, clinicians need to be increasingly aware of the precarious coagulation balance. The Authors. Published by Elsevier B.V. 2020-12 2020-08-12 /pmc/articles/PMC7419270/ /pubmed/32837915 http://dx.doi.org/10.1016/j.inat.2020.100878 Text en © 2020 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Case Reports & Case Series Khattar, Nicolas K. Sharma, Mayur McCallum, Abigail P. Oxford, Brent G. Zeb, Hassan Suliman, Sally A. Sieg, Emily P. Mocco, J Neimat, Joseph S. Zemmar, Ajmal Intracranial hemorrhage in a young COVID-19 patient |
title | Intracranial hemorrhage in a young COVID-19 patient |
title_full | Intracranial hemorrhage in a young COVID-19 patient |
title_fullStr | Intracranial hemorrhage in a young COVID-19 patient |
title_full_unstemmed | Intracranial hemorrhage in a young COVID-19 patient |
title_short | Intracranial hemorrhage in a young COVID-19 patient |
title_sort | intracranial hemorrhage in a young covid-19 patient |
topic | Case Reports & Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419270/ https://www.ncbi.nlm.nih.gov/pubmed/32837915 http://dx.doi.org/10.1016/j.inat.2020.100878 |
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