Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown

The thick mucus layer of the gut provides a barrier to infiltration of the underlying epithelia by both the normal microbiota and enteric pathogens. Some members of the microbiota utilise mucin glycoproteins as a nutrient source, but a detailed understanding of the mechanisms used to breakdown these...

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Detalles Bibliográficos
Autores principales: Crouch, Lucy I., Liberato, Marcelo V., Urbanowicz, Paulina A., Baslé, Arnaud, Lamb, Christopher A., Stewart, Christopher J., Cooke, Katie, Doona, Mary, Needham, Stephanie, Brady, Richard R., Berrington, Janet E., Madunic, Katarina, Wuhrer, Manfred, Chater, Peter, Pearson, Jeffery P., Glowacki, Robert, Martens, Eric C., Zhang, Fuming, Linhardt, Robert J., Spencer, Daniel I. R., Bolam, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419316/
https://www.ncbi.nlm.nih.gov/pubmed/32782292
http://dx.doi.org/10.1038/s41467-020-17847-5

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