Ischaemia with no obstructive coronary arteries

Ischaemia with no obstructive coronary arteries (INOCA) is a common ischaemic heart disease with a female preponderance, mostly due to underlying coronary vascular dysfunction comprising coronary microvascular dysfunction and/or epicardial coronary vasospasm. Since standard ischaemia detection tests...

Descripción completa

Detalles Bibliográficos
Autores principales: Konst, R. E., Meeder, J. G., Wittekoek, M. E., Maas, A. H. E. M., Appelman, Y., Piek, J. J., van de Hoef, T. P., Damman, P., Elias-Smale, S. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bohn Stafleu van Loghum 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419395/
https://www.ncbi.nlm.nih.gov/pubmed/32780334
http://dx.doi.org/10.1007/s12471-020-01451-9
_version_ 1783569875193561088
author Konst, R. E.
Meeder, J. G.
Wittekoek, M. E.
Maas, A. H. E. M.
Appelman, Y.
Piek, J. J.
van de Hoef, T. P.
Damman, P.
Elias-Smale, S. E.
author_facet Konst, R. E.
Meeder, J. G.
Wittekoek, M. E.
Maas, A. H. E. M.
Appelman, Y.
Piek, J. J.
van de Hoef, T. P.
Damman, P.
Elias-Smale, S. E.
author_sort Konst, R. E.
collection PubMed
description Ischaemia with no obstructive coronary arteries (INOCA) is a common ischaemic heart disease with a female preponderance, mostly due to underlying coronary vascular dysfunction comprising coronary microvascular dysfunction and/or epicardial coronary vasospasm. Since standard ischaemia detection tests and coronary angiograms are not suitable to diagnose coronary vascular dysfunction, INOCA is often overlooked in current cardiology practice. Future research, including large outcome trials, is much awaited. Yet, adequate diagnosis is possible and treatment options are available and vital to reduce symptoms and most probably improve cardiovascular prognosis. This review intends to give a brief overview of the clinical presentation, underlying pathophysiology, and the diagnostic and treatment options in patients with suspected INOCA.
format Online
Article
Text
id pubmed-7419395
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Bohn Stafleu van Loghum
record_format MEDLINE/PubMed
spelling pubmed-74193952020-08-18 Ischaemia with no obstructive coronary arteries Konst, R. E. Meeder, J. G. Wittekoek, M. E. Maas, A. H. E. M. Appelman, Y. Piek, J. J. van de Hoef, T. P. Damman, P. Elias-Smale, S. E. Neth Heart J Review Article Ischaemia with no obstructive coronary arteries (INOCA) is a common ischaemic heart disease with a female preponderance, mostly due to underlying coronary vascular dysfunction comprising coronary microvascular dysfunction and/or epicardial coronary vasospasm. Since standard ischaemia detection tests and coronary angiograms are not suitable to diagnose coronary vascular dysfunction, INOCA is often overlooked in current cardiology practice. Future research, including large outcome trials, is much awaited. Yet, adequate diagnosis is possible and treatment options are available and vital to reduce symptoms and most probably improve cardiovascular prognosis. This review intends to give a brief overview of the clinical presentation, underlying pathophysiology, and the diagnostic and treatment options in patients with suspected INOCA. Bohn Stafleu van Loghum 2020-08-11 2020-08 /pmc/articles/PMC7419395/ /pubmed/32780334 http://dx.doi.org/10.1007/s12471-020-01451-9 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Review Article
Konst, R. E.
Meeder, J. G.
Wittekoek, M. E.
Maas, A. H. E. M.
Appelman, Y.
Piek, J. J.
van de Hoef, T. P.
Damman, P.
Elias-Smale, S. E.
Ischaemia with no obstructive coronary arteries
title Ischaemia with no obstructive coronary arteries
title_full Ischaemia with no obstructive coronary arteries
title_fullStr Ischaemia with no obstructive coronary arteries
title_full_unstemmed Ischaemia with no obstructive coronary arteries
title_short Ischaemia with no obstructive coronary arteries
title_sort ischaemia with no obstructive coronary arteries
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419395/
https://www.ncbi.nlm.nih.gov/pubmed/32780334
http://dx.doi.org/10.1007/s12471-020-01451-9
work_keys_str_mv AT konstre ischaemiawithnoobstructivecoronaryarteries
AT meederjg ischaemiawithnoobstructivecoronaryarteries
AT wittekoekme ischaemiawithnoobstructivecoronaryarteries
AT maasahem ischaemiawithnoobstructivecoronaryarteries
AT appelmany ischaemiawithnoobstructivecoronaryarteries
AT piekjj ischaemiawithnoobstructivecoronaryarteries
AT vandehoeftp ischaemiawithnoobstructivecoronaryarteries
AT dammanp ischaemiawithnoobstructivecoronaryarteries
AT eliassmalese ischaemiawithnoobstructivecoronaryarteries

Ejemplares similares