Transcriptional mutagenesis dramatically alters genome-wide p53 transactivation landscape

The transcriptional error rate can be significantly increased by the presence of DNA lesions that instruct mis-insertion during transcription; a process referred to as transcriptional mutagenesis (TM) that can result in altered protein function. Herein, we determined the effect of O(6)-methylguanine...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Shuo, Ezerskyte, Monika, Wang, Jingwen, Pelechano, Vicent, Dreij, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419513/
https://www.ncbi.nlm.nih.gov/pubmed/32782319
http://dx.doi.org/10.1038/s41598-020-70412-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419513/
https://www.ncbi.nlm.nih.gov/pubmed/32782319
http://dx.doi.org/10.1038/s41598-020-70412-4

Ejemplares similares