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CRISPR/Cas12a mediated knock-in of the Polled Celtic variant to produce a polled genotype in dairy cattle

In modern livestock farming horned cattle pose an increased risk of injury for each other as well as for the farmers. Dehorning without anesthesia is associated with stress and pain for the calves and raises concerns regarding animal welfare. Naturally occurring structural variants causing pollednes...

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Detalles Bibliográficos
Autores principales: Schuster, Felix, Aldag, Patrick, Frenzel, Antje, Hadeler, Klaus-Gerd, Lucas-Hahn, Andrea, Niemann, Heiner, Petersen, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419524/
https://www.ncbi.nlm.nih.gov/pubmed/32782385
http://dx.doi.org/10.1038/s41598-020-70531-y