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Application of Fragment-Based Drug Discovery to Versatile Targets
Fragment-based drug discovery (FBDD) is a powerful method to develop potent small-molecule compounds starting from fragments binding weakly to targets. As FBDD exhibits several advantages over high-throughput screening campaigns, it becomes an attractive strategy in target-based drug discovery. Many...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419598/ https://www.ncbi.nlm.nih.gov/pubmed/32850968 http://dx.doi.org/10.3389/fmolb.2020.00180 |