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Wnt Signaling Inhibits High-Density Cell Sheet Culture Induced Mesenchymal Stromal Cell Aging by Targeting Cell Cycle Inhibitor p27

Mesenchymal stromal cell senescence and apoptosis have been identified as critical molecular hallmarks in aging. In this study, we used stromal cell sheet culture as an in vitro model to study the progressive changes of cellular senescence, apoptosis and underlying mechanism in Wnt3a treated cells....

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Detalles Bibliográficos
Autores principales:	Xu, Ying, Tian, Ye, Tong, Dongyi, Zhang, Hao, Luo, Zhengliang, Shang, Xifu, Dong, Yufeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419600/ https://www.ncbi.nlm.nih.gov/pubmed/32850766 http://dx.doi.org/10.3389/fbioe.2020.00946

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