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Hepatic Stellate Cells and Hepatocarcinogenesis

Hepatic stellate cells (HSCs) are a significant component of the hepatocellular carcinoma (HCC) tumor microenvironment (TME). Activated HSCs transform into myofibroblast-like cells to promote fibrosis in response to liver injury or chronic inflammation, leading to cirrhosis and HCC. The hepatic TME...

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Detalles Bibliográficos
Autores principales: Barry, Anna E., Baldeosingh, Rajkumar, Lamm, Ryan, Patel, Keyur, Zhang, Kai, Dominguez, Dana A., Kirton, Kayla J., Shah, Ashesh P., Dang, Hien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419619/
https://www.ncbi.nlm.nih.gov/pubmed/32850829
http://dx.doi.org/10.3389/fcell.2020.00709