Cargando…
Hepatic Stellate Cells and Hepatocarcinogenesis
Hepatic stellate cells (HSCs) are a significant component of the hepatocellular carcinoma (HCC) tumor microenvironment (TME). Activated HSCs transform into myofibroblast-like cells to promote fibrosis in response to liver injury or chronic inflammation, leading to cirrhosis and HCC. The hepatic TME...
Autores principales: | Barry, Anna E., Baldeosingh, Rajkumar, Lamm, Ryan, Patel, Keyur, Zhang, Kai, Dominguez, Dana A., Kirton, Kayla J., Shah, Ashesh P., Dang, Hien |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419619/ https://www.ncbi.nlm.nih.gov/pubmed/32850829 http://dx.doi.org/10.3389/fcell.2020.00709 |
Ejemplares similares
-
Hepatocellular Carcinoma—The Influence of Immunoanatomy and the Role of Immunotherapy
por: Patel, Keyur, et al.
Publicado: (2020) -
Disruption of FGF Signaling Ameliorates Inflammatory Response in Hepatic Stellate Cells
por: Wang, Cong, et al.
Publicado: (2020) -
A cAbl-MRTF-A Feedback Loop Contributes to Hepatic Stellate Cell Activation
por: Lu, Yunjie, et al.
Publicado: (2019) -
Down-Regulation of CXXC5 De-Represses MYCL1 to Promote Hepatic Stellate Cell Activation
por: Wu, Xiaoyan, et al.
Publicado: (2021) -
MicroRNA-98 Inhibits Hepatic Stellate Cell Activation and Attenuates Liver Fibrosis by Regulating HLF Expression
por: Wang, Qi, et al.
Publicado: (2020)