Cargando…
Proteoglycans as Therapeutic Targets in Brain Cancer
Proteoglycans (PGs) are heavily glycosylated diverse proteins consisting of a “core protein” covalently attached to glycosaminoglycans (GAGs) and present on the cell surface, extracellular matrix, and intracellular milieu. Extracellular proteoglycans play crucial roles in facilitating cell signaling...
Autores principales: | Yan, Zoya, Wang, Shanzhi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419654/ https://www.ncbi.nlm.nih.gov/pubmed/32850434 http://dx.doi.org/10.3389/fonc.2020.01358 |
Ejemplares similares
-
Editorial: Heparan Sulfate Proteoglycans and Their Endogenous Modifying Enzymes: Cancer Players, Biomarkers and Therapeutic Targets
por: Lanzi, Cinzia, et al.
Publicado: (2020) -
Editorial: Proteoglycans in the Tumor Microenvironment
por: Brunetti, Jlenia, et al.
Publicado: (2022) -
Expression and Role of Heparan Sulfated Proteoglycans in Pancreatic Cancer
por: Furini, Simone, et al.
Publicado: (2021) -
The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics
por: Hammond, Edward, et al.
Publicado: (2014) -
Chondroitin sulfate proteoglycan 4 expression in chondrosarcoma: A potential target for antibody-based immunotherapy
por: Nota, Sjoerd P. F. T., et al.
Publicado: (2022)