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Targeting MDMX for Cancer Therapy: Rationale, Strategies, and Challenges

The oncogene MDMX, also known as MDM4 is a critical negative regulator of the tumor suppressor p53 and has been implicated in the initiation and progression of human cancers. Increasing evidence indicates that MDMX is often amplified and highly expressed in human cancers, promotes cancer cell growth...

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Detalles Bibliográficos
Autores principales:	Yu, De-Hua, Xu, Zhi-Yuan, Mo, Shaowei, Yuan, Li, Cheng, Xiang-Dong, Qin, Jiang-Jiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419686/ https://www.ncbi.nlm.nih.gov/pubmed/32850448 http://dx.doi.org/10.3389/fonc.2020.01389

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