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Sustained Activation of AMPK Enhances Differentiation of Human iPSC-Derived Cardiomyocytes via Sirtuin Activation

Recent studies suggest that metabolic regulation may improve differentiation of cardiomyocytes derived from induced pluripotent stem cells (iPSCs). AMP-activated protein kinase (AMPK) is a master regulator of metabolic activities. We investigated whether AMPK participates in iPSC-derived cardiomyocy...

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Detalles Bibliográficos
Autores principales:	Sarikhani, Mohsen, Garbern, Jessica C., Ma, Sai, Sereda, Rebecca, Conde, Jeffrey, Krähenbühl, Guido, Escalante, Gabriela O., Ahmed, Aishah, Buenrostro, Jason D., Lee, Richard T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419706/ https://www.ncbi.nlm.nih.gov/pubmed/32649901 http://dx.doi.org/10.1016/j.stemcr.2020.06.012

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