Increased Expression of Interleukin-1 Receptor Characterizes Anti-estrogen-Resistant ALDH(+) Breast Cancer Stem Cells

Estrogen-receptor-positive breast tumors are treated with anti-estrogen (AE) therapies but frequently develop resistance. Cancer stem cells (CSCs) with high aldehyde dehydrogenase activity (ALDH(+) cells) are enriched following AE treatment. Here, we show that the interleukin-1β (IL-1β) signaling pa...

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Detalles Bibliográficos
Autores principales: Sarmiento-Castro, Aida, Caamaño-Gutiérrez, Eva, Sims, Andrew H., Hull, Nathan J., James, Mark I., Santiago-Gómez, Angélica, Eyre, Rachel, Clark, Christopher, Brown, Martha E., Brooks, Michael D., Wicha, Max S., Howell, Sacha J., Clarke, Robert B., Simões, Bruno M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419713/
https://www.ncbi.nlm.nih.gov/pubmed/32707076
http://dx.doi.org/10.1016/j.stemcr.2020.06.020

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