Cladribine modifies functional properties of microglia

Cladribine (CdA), an oral prodrug approved for the treatment of relapsing multiple sclerosis, selectively depletes lymphocytes. CdA passes the blood–brain barrier, suggesting a potential effect on central nervous system (CNS) resident cells. We examined if CdA modifies the phenotype and function of...

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Detalles Bibliográficos
Autores principales: Jørgensen, L. Ø., Hyrlov, K. H., Elkjaer, M. L., Weber, A. B., Pedersen, A. E., Svenningsen, Å. Fex, Illes, Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419928/
https://www.ncbi.nlm.nih.gov/pubmed/32492189
http://dx.doi.org/10.1111/cei.13473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419928/
https://www.ncbi.nlm.nih.gov/pubmed/32492189
http://dx.doi.org/10.1111/cei.13473

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