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Cladribine modifies functional properties of microglia
Cladribine (CdA), an oral prodrug approved for the treatment of relapsing multiple sclerosis, selectively depletes lymphocytes. CdA passes the blood–brain barrier, suggesting a potential effect on central nervous system (CNS) resident cells. We examined if CdA modifies the phenotype and function of...
Autores principales: | Jørgensen, L. Ø., Hyrlov, K. H., Elkjaer, M. L., Weber, A. B., Pedersen, A. E., Svenningsen, Å. Fex, Illes, Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419928/ https://www.ncbi.nlm.nih.gov/pubmed/32492189 http://dx.doi.org/10.1111/cei.13473 |
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