Cargando…

Bergenin Reduces Experimental Painful Diabetic Neuropathy by Restoring Redox and Immune Homeostasis in the Nervous System

Diabetic neuropathy is a frequent complication of diabetes. Symptoms include neuropathic pain and sensory alterations—no effective treatments are currently available. This work characterized the therapeutic effect of bergenin in a mouse (C57/BL6) model of streptozotocin-induced painful diabetic neur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Villarreal, Cristiane F., Santos, Dourivaldo S., Lauria, Pedro S. S., Gama, Kelly B., Espírito-Santo, Renan F., Juiz, Paulo J. L., Alves, Clayton Q., David, Jorge M., Soares, Milena B. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7420298/ https://www.ncbi.nlm.nih.gov/pubmed/32659952 http://dx.doi.org/10.3390/ijms21144850

Ejemplares similares

Reestablishment of Redox Homeostasis in the Nociceptive Primary Afferent as a Mechanism of Antinociception Promoted by Mesenchymal Stem/Stromal Cells in Oxaliplatin-Induced Chronic Peripheral Neuropathy
por: Oliveira, Anna Lethicia L., et al.
Publicado: (2021)

Chemistry and Pharmacology of Bergenin or Its Derivatives: A Promising Molecule
por: Salimo, Zeca M., et al.
Publicado: (2023)

Unveiling Targets for Treating Postoperative Pain: The Role of the TNF-α/p38 MAPK/NF-κB/Nav1.8 and Nav1.9 Pathways in the Mouse Model of Incisional Pain
por: de Lima, Flávia Oliveira, et al.
Publicado: (2022)

Bergenin as a Novel Urate-Lowering Therapeutic Strategy for Hyperuricemia
por: Chen, Mo, et al.
Publicado: (2020)

Conditioned Medium of Bone Marrow-Derived Mesenchymal Stromal Cells as a Therapeutic Approach to Neuropathic Pain: A Preclinical Evaluation
por: Gama, Kelly Barbosa, et al.
Publicado: (2018)

Cell-free therapy: a neuroregenerative approach to sensory neuropathy?
por: Evangelista, Afrânio Ferreira, et al.
Publicado: (2019)

Use of bergenin as an analytical marker for standardization of the polyherbal formulation containing Saxifraga ligulata
por: Pushpalatha, Hulikal Basavarajaiah, et al.
Publicado: (2015)

Bergenin determination in different extracts by high-performance thin-layer chromatographic densitometry
por: Khan, Masood Shah, et al.
Publicado: (2015)

In vitro inhibitory effects of bergenin on human liver cytochrome P450 enzymes
por: Dong, Gang, et al.
Publicado: (2018)

Targeting Mcl-1 Degradation by Bergenin Inhibits Tumorigenesis of Colorectal Cancer Cells
por: Gan, Yu, et al.
Publicado: (2023)

Antioxidant and Antiplasmodial Activities of Bergenin and 11-O-Galloylbergenin Isolated from Mallotus philippensis
por: Khan, Hamayun, et al.
Publicado: (2016)

Design and Evaluation of pH-Sensitive Nanoformulation of Bergenin Isolated from Bergenia ciliata
por: Bashir, Kashaf, et al.
Publicado: (2022)

Bergenin ameliorates cognitive deficits and neuropathological alterations in sodium azide-induced experimental dementia
por: Singla, Rajeev K., et al.
Publicado: (2022)

Effect of Bergenin on Human Gingival Fibroblast Response on Zirconia Implant Surfaces: An In Vitro Study
por: Xiong, John, et al.
Publicado: (2023)

Bone marrow-derived mesenchymal stem/stromal cells reverse the sensorial diabetic neuropathy via modulation of spinal neuroinflammatory cascades
por: Evangelista, Afrânio Ferreira, et al.
Publicado: (2018)

(E)-2-Cyano-3-(1H-Indol-3-yl)-N-Phenylacrylamide, a Hybrid Compound Derived from Indomethacin and Paracetamol: Design, Synthesis and Evaluation of the Anti-Inflammatory Potential
por: Silva, Pablo, et al.
Publicado: (2020)

Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway
por: Xia, Yujing, et al.
Publicado: (2020)

p62-Nrf2 Regulatory Loop Mediates the Anti-Pulmonary Fibrosis Effect of Bergenin
por: Zeng, Qian, et al.
Publicado: (2022)

Vasorelaxant and Antihypertensive Effects of Bergenin on Isolated Rat Aorta and High Salt-Induced Hypertensive Rats
por: Ahmad, Taseer, et al.
Publicado: (2022)

The Effect of Bergenin on Isonicotinic Acid Hydrazide and Rifampicin-Induced Liver Injury Revealed by RNA Sequencing
por: Li, Ting, et al.
Publicado: (2023)

Pharmacological Properties of Riparin IV in Models of Pain and Inflammation
por: Nascimento, Olívia Azevêdo, et al.
Publicado: (2016)

The Emerging Role of Estrogens in Thyroid Redox Homeostasis and Carcinogenesis
por: Faria, Caroline C., et al.
Publicado: (2019)

Antioxidant Defences and Redox Homeostasis in Animals
por: Surai, Peter F., et al.
Publicado: (2022)

Cellular Redox Homeostasis
por: Le Gal, Kristell, et al.
Publicado: (2021)

Exerkines and redox homeostasis
por: Félix-Soriano, Elisa, et al.
Publicado: (2023)

Isolation of bergenin from the root bark of Securinega virosa and evaluation of its potential sleep promoting effect
por: Magaji, Mohammed Garba, et al.
Publicado: (2015)

Protective Effect of Bergenin against Cyclophosphamide-Induced Immunosuppression by Immunomodulatory Effect and Antioxidation in Balb/c Mice
por: Qi, Qiuchen, et al.
Publicado: (2018)

Bergenin Activates SIRT1 as a Novel Therapeutic Agent for Osteogenesis of Bone Mesenchymal Stem Cells
por: Hou, Weiduo, et al.
Publicado: (2019)

Bergenin protects pancreatic beta cells against cytokine-induced apoptosis in INS-1E cells
por: Rajput, Sajid Ali, et al.
Publicado: (2020)

Exploring the hypolipidemic effects of bergenin from Saxifraga melanocentra Franch: mechanistic insights and potential for hyperlipidemia treatment
por: Zhang, Li, et al.
Publicado: (2023)

A New Insight into an Alternative Therapeutic Approach to Restore Redox Homeostasis and Functional Mitochondria in Neurodegenerative Diseases
por: Hyun, Dong-Hoon, et al.
Publicado: (2021)

Ginsenosides Restore Lipid and Redox Homeostasis in Mice with Intrahepatic Cholestasis through SIRT1/AMPK Pathways
por: Li, Guodong, et al.
Publicado: (2022)

Kartogenin-enhanced dynamic hydrogel ameliorates intervertebral disc degeneration via restoration of local redox homeostasis
por: Tian, Xin, et al.
Publicado: (2023)

The Phytochemical Bergenin Enhances T Helper 1 Responses and Anti-Mycobacterial Immunity by Activating the MAP Kinase Pathway in Macrophages
por: Dwivedi, Ved P., et al.
Publicado: (2017)

Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway
por: Xiang, Shihao, et al.
Publicado: (2020)

Redox regulated peroxisome homeostasis
por: Wang, Xiaofeng, et al.
Publicado: (2014)

Editorial: Redox Homeostasis and Cancer
por: Sinha, Mithun, et al.
Publicado: (2020)

Hsp70 in Redox Homeostasis
por: Zhang, Hong, et al.
Publicado: (2022)

Redox Homeostasis in Muscular Dystrophies
por: Mosca, Nicola, et al.
Publicado: (2021)

Glutathione and peroxisome redox homeostasis
por: Ferreira, Maria J., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_i0q50fhbl53oif9ucm2lc20r2m