Cargando…

A Multiple Primary Malignancy Patient With FANCA Gene Mutation: A Case Report and Literature Review

Background: Multiple primary malignancies (MPMs) refer to two or more primary malignant tumors in the same individual, the prevalence of which ranges from 0. 734 to 11.7%. The risk factors for MPMs vary and include both genetic and environmental causes. FANCA gene mutation might be a predisposition...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xia, Qing, Zhao, Ling-Yi, Yan, Yi-Dan, Liao, Yuan, Di, Ying-San, Xiao, Xiu-Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7420727/ https://www.ncbi.nlm.nih.gov/pubmed/32850347 http://dx.doi.org/10.3389/fonc.2020.01199

Ejemplares similares

Clinical Benefit With PARP Inhibitor for Pathogenic Germline FANCA-Mutated Relapsed Epithelial Ovarian Cancer: A Case Report
por: Qian, Bing, et al.
Publicado: (2022)

Durable response to olaparib combined low-dose cisplatin in advanced hepatocellular carcinoma with FANCA mutation: A case report
por: Lai, Yi-Hsuan, et al.
Publicado: (2022)

FANCA Gene Mutations in North African Fanconi Anemia Patients
por: Ben Haj Ali, Abir, et al.
Publicado: (2021)

FANCA D1359Y mutation in a patient with gastric polyposis and cancer susceptibility: A case report and review of literature
por: Huang, Jeffrey Peng, et al.
Publicado: (2018)

Multiple primary malignant neoplasm: Case report and comprehensive literature review
por: Ma, Xue-Yan, et al.
Publicado: (2023)

Hypomorphic FANCA mutations correlate with mild mitochondrial and clinical phenotype in Fanconi anemia
por: Bottega, Roberta, et al.
Publicado: (2018)

Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex
por: Jeong, Eunyoung, et al.
Publicado: (2020)

Rare variants in FANCA induce premature ovarian insufficiency
por: Yang, Xi, et al.
Publicado: (2019)

Coregulation of FANCA and BRCA1 in human cells
por: Haitjema, Anneke, et al.
Publicado: (2014)

The role of (18)F-FDG PET/CT in patients with synchronous multiple primary malignant neoplasms occurring at the same time
por: Luo, Zhe Huang, et al.
Publicado: (2022)

FANCA Gene Mutations with 8 Novel Molecular Changes in Indian Fanconi Anemia Patients
por: Solanki, Avani, et al.
Publicado: (2016)

Investigation of FANCA gene in Fanconi anaemia patients in Iran
por: Saffar Moghadam, Ali Akbar, et al.
Publicado: (2016)

FANCA deficiency promotes leukaemic progression by allowing the emergence of cells carrying oncogenic driver mutations
por: Pawlikowska, Patrycja, et al.
Publicado: (2023)

FANCA Polymorphism Is Associated with the Rate of Proliferation in Uterine Leiomyoma in Korea
por: Ha, Eunyoung, et al.
Publicado: (2020)

Fanca deficiency is associated with alterations in osteoclastogenesis that are rescued by TNFα
por: Oppezzo, Alessia, et al.
Publicado: (2023)

Treatment of Multiple Primary Malignancies With PD-1 Inhibitor Camrelizumab: A Case Report and Brief Literature Review
por: Wan, Yuchen, et al.
Publicado: (2022)

Identification of Three Novel Mutations in the FANCA, FANCC, and ITGA2B Genes by Whole Exome Sequencing
por: Negahdari, Samira, et al.
Publicado: (2020)

Novel FANCA mutation in the first fully-diagnosed patient with Fanconi anemia in Polish population – case report
por: Repczynska, Anna, et al.
Publicado: (2020)

Altered Mitochondrial Dynamic in Lymphoblasts and Fibroblasts Mutated for FANCA-A Gene: The Central Role of DRP1
por: Bertola, Nadia, et al.
Publicado: (2023)

A Female With Synchronous Multiple Primary Malignant Tumors in the Esophagogastric Junction, Duodenum and Pancreas: Case Report and Review of the Literature
por: Du, Yongxing, et al.
Publicado: (2022)

Treatment of FANCA Cells with Resveratrol and N-Acetylcysteine: A Comparative Study
por: Columbaro, Marta, et al.
Publicado: (2014)

Mutated FANCA Gene Role in the Modulation of Energy Metabolism and Mitochondrial Dynamics in Head and Neck Squamous Cell Carcinoma
por: Bertola, Nadia, et al.
Publicado: (2022)

SIK2 kinase synthetic lethality is driven by spindle assembly defects in FANCA‐deficient cells
por: Chan, Ka‐Kui, et al.
Publicado: (2021)

Case report: ISL2 is involved in malignant transformation in a patient with multiple relapsed oligodendroglioma
por: Chen, Shu-Na, et al.
Publicado: (2022)

Risk and prediction of multiple primary malignancies after early gastric cancer
por: Chen, Na, et al.
Publicado: (2023)

Preliminary study on the molecular features of mutation in multiple primary oral cancer by whole exome sequencing
por: Li, Kan, et al.
Publicado: (2022)

Synchronous multiple primary malignancies of clear cell renal cell carcinoma with sarcomatoid, thyroid carcinoma: a case report
por: Tan, Yaxian, et al.
Publicado: (2023)

Does FANCA Assist CENP-E in Architectural Organization of Chromosomes at Spindle Equator?
por: El-Arabey, Amr Ahmed, et al.
Publicado: (2018)

A germline FANCA alteration that is associated with increased sensitivity to DNA damaging agents
por: Wilkes, David C., et al.
Publicado: (2017)

Analysis of Overall Survival in Patients With Multiple Primary Malignancies: A Single-center Experience
por: Skelton, William P, et al.
Publicado: (2019)

Risk of Second Primary Cancers Among Long-Term Survivors of Breast Cancer
por: Li, Dan, et al.
Publicado: (2020)

Novel Founder Mutation in FANCA Gene (c.3446_3449dupCCCT) Among Romani Patients from the Balkan Region
por: Dimishkovska, Marija, et al.
Publicado: (2018)

What Are the Results of Limb Salvage Surgery for Primary Malignant Bone Tumor in the Forearm?
por: Liu, Weifeng, et al.
Publicado: (2022)

Primary renal malignant epithelioid angiomyolipoma with distant metastasis: a case report and literature review
por: Zhang, Jun, et al.
Publicado: (2023)

A novel duplication polymorphism in the FANCA promoter and its association with breast and ovarian cancer
por: Thompson, Ella, et al.
Publicado: (2005)

Esophageal cancer as initial presentation of Fanconi anemia in patients with a hypomorphic FANCA variant
por: Lach, Francis P., et al.
Publicado: (2020)

Multiple Primary Malignant Neoplasms: An Unusual Case of Metachronous Breast Ductal and Squamous Cell Carcinomas
por: Ibrahim, Mohd Elmugtaba, et al.
Publicado: (2020)

Case Report: Malignant Brain Tumors in Siblings With MSH6 Mutations
por: Wu, Di, et al.
Publicado: (2022)

Distinct gene mutation profiles among multiple and single primary lung adenocarcinoma
por: Wang, Yadong, et al.
Publicado: (2022)

PHF6 Mutations in Hematologic Malignancies
por: Kurzer, Jason H., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_luu0vku6bgjp2l9130uosp5srf