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Kupffer Cell-Derived TNF-α Triggers the Apoptosis of Hepatic Stellate Cells through TNF-R1/Caspase 8 due to ER Stress

PURPOSE: To investigate the roles of ER stress in Kupffer cells (KCs) and KC-derived TNF-α in the apoptosis of hepatic stellate cells (HSCs). METHODS: A rat model of liver fibrosis was established. Liver and blood serum samples were collected. Liver function assays, Masson staining, Sirius Red stain...

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Detalles Bibliográficos
Autores principales:	Wang, Wei-min, Xu, Xue-song, Miao, Chun-mu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7421237/ https://www.ncbi.nlm.nih.gov/pubmed/32802876 http://dx.doi.org/10.1155/2020/8035671

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