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Risk factors associated with the severity of obstructive sleep apnea syndrome among adults
Obstructive sleep apnea syndrome (OSAS) is a complete or partial airway obstruction that causes significant physiologic disturbance with various clinical impacts. The aim of the study was to determine the risk factors associated with the severity of OSAS. 303 patients with OSAS and 199 patients with...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7421897/ https://www.ncbi.nlm.nih.gov/pubmed/32782271 http://dx.doi.org/10.1038/s41598-020-70286-6 |
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author | Zhou, Xiaobo Lu, Qiao Li, Shaoping Pu, Zhongyin Gao, Fang Zhou, Bo |
author_facet | Zhou, Xiaobo Lu, Qiao Li, Shaoping Pu, Zhongyin Gao, Fang Zhou, Bo |
author_sort | Zhou, Xiaobo |
collection | PubMed |
description | Obstructive sleep apnea syndrome (OSAS) is a complete or partial airway obstruction that causes significant physiologic disturbance with various clinical impacts. The aim of the study was to determine the risk factors associated with the severity of OSAS. 303 patients with OSAS and 199 patients without OSAS enrolled in the sleep disorder center from 2017 to 2019 were included in the study. All patients completed physical examination, Epworth sleepiness scale, and polysomnography. By apnea–hypopnea index (AHI), patients were separated into four subsets: AHI < 5 as non-OSAS group, AHI ≧ 5 and < 15 as mild group, AHI ≧ 15 and < 30 as moderate group and AHI ≧ 30 as severe group. AVONA analyses, chi-square test, univariate and multivariate linear regression analyses were conducted to assess the correlation between specific factors and AHI. Our study demonstrated that patients with severe OSAS were associated with higher body mass index, higher systolic blood pressure awake in the morning, lengthened latent period of slow wave sleep, lower level of average oxygen saturation and minimum oxygen saturation (P < 0.05). Our findings provide evidence regarding several potentially useful factors for recognizing OSAS in adults, and physicians should promote the early recognition, diagnosis and intervention of OSAS. |
format | Online Article Text |
id | pubmed-7421897 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-74218972020-08-13 Risk factors associated with the severity of obstructive sleep apnea syndrome among adults Zhou, Xiaobo Lu, Qiao Li, Shaoping Pu, Zhongyin Gao, Fang Zhou, Bo Sci Rep Article Obstructive sleep apnea syndrome (OSAS) is a complete or partial airway obstruction that causes significant physiologic disturbance with various clinical impacts. The aim of the study was to determine the risk factors associated with the severity of OSAS. 303 patients with OSAS and 199 patients without OSAS enrolled in the sleep disorder center from 2017 to 2019 were included in the study. All patients completed physical examination, Epworth sleepiness scale, and polysomnography. By apnea–hypopnea index (AHI), patients were separated into four subsets: AHI < 5 as non-OSAS group, AHI ≧ 5 and < 15 as mild group, AHI ≧ 15 and < 30 as moderate group and AHI ≧ 30 as severe group. AVONA analyses, chi-square test, univariate and multivariate linear regression analyses were conducted to assess the correlation between specific factors and AHI. Our study demonstrated that patients with severe OSAS were associated with higher body mass index, higher systolic blood pressure awake in the morning, lengthened latent period of slow wave sleep, lower level of average oxygen saturation and minimum oxygen saturation (P < 0.05). Our findings provide evidence regarding several potentially useful factors for recognizing OSAS in adults, and physicians should promote the early recognition, diagnosis and intervention of OSAS. Nature Publishing Group UK 2020-08-11 /pmc/articles/PMC7421897/ /pubmed/32782271 http://dx.doi.org/10.1038/s41598-020-70286-6 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Zhou, Xiaobo Lu, Qiao Li, Shaoping Pu, Zhongyin Gao, Fang Zhou, Bo Risk factors associated with the severity of obstructive sleep apnea syndrome among adults |
title | Risk factors associated with the severity of obstructive sleep apnea syndrome among adults |
title_full | Risk factors associated with the severity of obstructive sleep apnea syndrome among adults |
title_fullStr | Risk factors associated with the severity of obstructive sleep apnea syndrome among adults |
title_full_unstemmed | Risk factors associated with the severity of obstructive sleep apnea syndrome among adults |
title_short | Risk factors associated with the severity of obstructive sleep apnea syndrome among adults |
title_sort | risk factors associated with the severity of obstructive sleep apnea syndrome among adults |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7421897/ https://www.ncbi.nlm.nih.gov/pubmed/32782271 http://dx.doi.org/10.1038/s41598-020-70286-6 |
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