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Relationship of the neutrophil/lymphocyte ratio with cardiovascular risk markers in premenopausal and postmenopausal women

INTRODUCTION: Cardiovascular disease is more frequent in postmenopausal women. Atherosclerosis is associated with inflammation and the neutrophil/lymphocyte ratio (NLR) is a marker of inflammation whose behavior in postmenopause is unknown. AIM OF THE STUDY: To know the relationship of the NLR with...

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Autores principales: Carranza-Lira, Sebastián, Montiel, Maryel Montes, Camacho, Karina Ocampo, Santana, Xiomara Hernández, Ortiz, Sergio Rosales, Muñoz, Eunice López, Ángeles, Luis Claudio Erick Hernández
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422287/
https://www.ncbi.nlm.nih.gov/pubmed/32802014
http://dx.doi.org/10.5114/pm.2020.97835
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author Carranza-Lira, Sebastián
Montiel, Maryel Montes
Camacho, Karina Ocampo
Santana, Xiomara Hernández
Ortiz, Sergio Rosales
Muñoz, Eunice López
Ángeles, Luis Claudio Erick Hernández
author_facet Carranza-Lira, Sebastián
Montiel, Maryel Montes
Camacho, Karina Ocampo
Santana, Xiomara Hernández
Ortiz, Sergio Rosales
Muñoz, Eunice López
Ángeles, Luis Claudio Erick Hernández
author_sort Carranza-Lira, Sebastián
collection PubMed
description INTRODUCTION: Cardiovascular disease is more frequent in postmenopausal women. Atherosclerosis is associated with inflammation and the neutrophil/lymphocyte ratio (NLR) is a marker of inflammation whose behavior in postmenopause is unknown. AIM OF THE STUDY: To know the relationship of the NLR with cardiovascular risk markers in premenopausal and postmenopausal women. MATERIAL AND METHODS: Premenopausal and postmenopausal women were studied, in all of them a complete hemogram and the NLR, platelet/lymphocyte ratio (PLR) were calculated, also glucose and lipids levels were measured. In all of them subcutaneous and visceral fat, carotid intima-media thickness (IMT), epicardial fat were measured by ultrasound Also baseline and and after flow-mediated stimulus the arterial diameter, the pulsatility index and the resistive index of the brachial artery were measured by ultrasound. The results are reported with medians and intervals, Mann-Whitney U and Spearman correlation analysis were performed. RESULTS: Eighty two patients were recruited, 41 premenopausal and 41 postmenopausal. When comparing both groups there was no difference in glucose, lipids, NLR, PLR, carotid IMT, epicardial fat, subcutaneous fat, visceral fat or Doppler parameters of the brachial artery. CONCLUSION: NLR was not different between premenopausal and postmenopausal women but abnormal PLR was greater in those postmenopausal with vasomotor symptoms.
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spelling pubmed-74222872020-08-14 Relationship of the neutrophil/lymphocyte ratio with cardiovascular risk markers in premenopausal and postmenopausal women Carranza-Lira, Sebastián Montiel, Maryel Montes Camacho, Karina Ocampo Santana, Xiomara Hernández Ortiz, Sergio Rosales Muñoz, Eunice López Ángeles, Luis Claudio Erick Hernández Prz Menopauzalny Original Paper INTRODUCTION: Cardiovascular disease is more frequent in postmenopausal women. Atherosclerosis is associated with inflammation and the neutrophil/lymphocyte ratio (NLR) is a marker of inflammation whose behavior in postmenopause is unknown. AIM OF THE STUDY: To know the relationship of the NLR with cardiovascular risk markers in premenopausal and postmenopausal women. MATERIAL AND METHODS: Premenopausal and postmenopausal women were studied, in all of them a complete hemogram and the NLR, platelet/lymphocyte ratio (PLR) were calculated, also glucose and lipids levels were measured. In all of them subcutaneous and visceral fat, carotid intima-media thickness (IMT), epicardial fat were measured by ultrasound Also baseline and and after flow-mediated stimulus the arterial diameter, the pulsatility index and the resistive index of the brachial artery were measured by ultrasound. The results are reported with medians and intervals, Mann-Whitney U and Spearman correlation analysis were performed. RESULTS: Eighty two patients were recruited, 41 premenopausal and 41 postmenopausal. When comparing both groups there was no difference in glucose, lipids, NLR, PLR, carotid IMT, epicardial fat, subcutaneous fat, visceral fat or Doppler parameters of the brachial artery. CONCLUSION: NLR was not different between premenopausal and postmenopausal women but abnormal PLR was greater in those postmenopausal with vasomotor symptoms. Termedia Publishing House 2020-07-13 2020-07 /pmc/articles/PMC7422287/ /pubmed/32802014 http://dx.doi.org/10.5114/pm.2020.97835 Text en Copyright © 2020 Termedia http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0). License (http://creativecommons.org/licenses/by-nc-sa/4.0/)
spellingShingle Original Paper
Carranza-Lira, Sebastián
Montiel, Maryel Montes
Camacho, Karina Ocampo
Santana, Xiomara Hernández
Ortiz, Sergio Rosales
Muñoz, Eunice López
Ángeles, Luis Claudio Erick Hernández
Relationship of the neutrophil/lymphocyte ratio with cardiovascular risk markers in premenopausal and postmenopausal women
title Relationship of the neutrophil/lymphocyte ratio with cardiovascular risk markers in premenopausal and postmenopausal women
title_full Relationship of the neutrophil/lymphocyte ratio with cardiovascular risk markers in premenopausal and postmenopausal women
title_fullStr Relationship of the neutrophil/lymphocyte ratio with cardiovascular risk markers in premenopausal and postmenopausal women
title_full_unstemmed Relationship of the neutrophil/lymphocyte ratio with cardiovascular risk markers in premenopausal and postmenopausal women
title_short Relationship of the neutrophil/lymphocyte ratio with cardiovascular risk markers in premenopausal and postmenopausal women
title_sort relationship of the neutrophil/lymphocyte ratio with cardiovascular risk markers in premenopausal and postmenopausal women
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422287/
https://www.ncbi.nlm.nih.gov/pubmed/32802014
http://dx.doi.org/10.5114/pm.2020.97835
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