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Kras mutations and PU.1 promoter methylation are new pathways in murine radiation-induced AML

Therapy-related and more specifically radiotherapy-associated acute myeloid leukaemia (AML) is a well-recognized potential complication of cytotoxic therapy for the treatment of a primary cancer. The CBA mouse model is used to study radiation leukaemogenesis mechanisms with Sfpi1/PU.1 deletion and p...

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Detalles Bibliográficos
Autores principales:	O’Brien, Gráinne, Cruz-Garcia, Lourdes, Zyla, Joanna, Brown, Natalie, Finnon, Rosemary, Polanska, Joanna, Badie, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Carcinogenesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422620/ https://www.ncbi.nlm.nih.gov/pubmed/31646336 http://dx.doi.org/10.1093/carcin/bgz175

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