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Decellularizing the Porcine Optic Nerve Head: Toward a Model to Study the Mechanobiology of Glaucoma

PURPOSE: Studying the extracellular matrix (ECM) remodeling of the lamina cribrosa in vivo can be extremely challenging and costly. There exist very few options for studying optic nerve head (ONH) mechanobiology in vitro that are able to reproduce the complex anatomic and biomechanical environment o...

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Detalles Bibliográficos
Autores principales: Liou, Jr-Jiun, Drewry, Michelle D., Sweeney, Ashlinn, Brown, Bryan N., Vande Geest, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422887/
https://www.ncbi.nlm.nih.gov/pubmed/32855864
http://dx.doi.org/10.1167/tvst.9.8.17