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PnPP-19 Peptide as a Novel Drug Candidate for Topical Glaucoma Therapy Through Nitric Oxide Release

PURPOSE: Evaluation of PnPP-19 safety and efficacy in reducing the intraocular pressure (IOP) of animals with healthy (normotensive) and ocular hypertensive eyes. PnPP-19 is a synthetic peptide designed from Phoneutria nigriventer spider toxin PnTx2-6. METHODS: Toxicity tests used chicken chorioalla...

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Detalles Bibliográficos
Autores principales:	da Silva, Carolina Nunes, Dourado, Lays Fernanda Nunes, de Lima, Maria Elena, da Silva Cunha-Jr, Armando
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422904/ https://www.ncbi.nlm.nih.gov/pubmed/32855879 http://dx.doi.org/10.1167/tvst.9.8.33

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