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RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases

Mitochondrial translation defects can be due to mutations affecting mitochondrial- or nuclear-encoded components. The number of known nuclear genes involved in mitochondrial translation has significantly increased in the past years. RCC1L (WBSCR16), a putative GDP/GTP exchange factor, has recently b...

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Detalles Bibliográficos
Autores principales: Reyes, Aurelio, Favia, Paola, Vidoni, Sara, Petruzzella, Vittoria, Zeviani, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423155/
https://www.ncbi.nlm.nih.gov/pubmed/32735630
http://dx.doi.org/10.1371/journal.pgen.1008923