Cargando…
Antibiotics and Innate Immunity: A Cooperative Effort Toward the Successful Treatment of Infections
Despite the common ancestry of antimicrobial and immunological science, a divergence driven by artificially construed paradigms in microbiology has placed limits on how we understand the mechanisms of antibiotics in vivo. We summarize recent updates on data that shed light on how antibiotics interac...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423293/ https://www.ncbi.nlm.nih.gov/pubmed/32818143 http://dx.doi.org/10.1093/ofid/ofaa302 |
_version_ | 1783570146914205696 |
---|---|
author | Berti, Andrew Rose, Warren Nizet, Victor Sakoulas, George |
author_facet | Berti, Andrew Rose, Warren Nizet, Victor Sakoulas, George |
author_sort | Berti, Andrew |
collection | PubMed |
description | Despite the common ancestry of antimicrobial and immunological science, a divergence driven by artificially construed paradigms in microbiology has placed limits on how we understand the mechanisms of antibiotics in vivo. We summarize recent updates on data that shed light on how antibiotics interact with components of innate immunity. |
format | Online Article Text |
id | pubmed-7423293 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-74232932020-08-17 Antibiotics and Innate Immunity: A Cooperative Effort Toward the Successful Treatment of Infections Berti, Andrew Rose, Warren Nizet, Victor Sakoulas, George Open Forum Infect Dis Perspectives Despite the common ancestry of antimicrobial and immunological science, a divergence driven by artificially construed paradigms in microbiology has placed limits on how we understand the mechanisms of antibiotics in vivo. We summarize recent updates on data that shed light on how antibiotics interact with components of innate immunity. Oxford University Press 2020-07-20 /pmc/articles/PMC7423293/ /pubmed/32818143 http://dx.doi.org/10.1093/ofid/ofaa302 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Perspectives Berti, Andrew Rose, Warren Nizet, Victor Sakoulas, George Antibiotics and Innate Immunity: A Cooperative Effort Toward the Successful Treatment of Infections |
title | Antibiotics and Innate Immunity: A Cooperative Effort Toward the Successful Treatment of Infections |
title_full | Antibiotics and Innate Immunity: A Cooperative Effort Toward the Successful Treatment of Infections |
title_fullStr | Antibiotics and Innate Immunity: A Cooperative Effort Toward the Successful Treatment of Infections |
title_full_unstemmed | Antibiotics and Innate Immunity: A Cooperative Effort Toward the Successful Treatment of Infections |
title_short | Antibiotics and Innate Immunity: A Cooperative Effort Toward the Successful Treatment of Infections |
title_sort | antibiotics and innate immunity: a cooperative effort toward the successful treatment of infections |
topic | Perspectives |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423293/ https://www.ncbi.nlm.nih.gov/pubmed/32818143 http://dx.doi.org/10.1093/ofid/ofaa302 |
work_keys_str_mv | AT bertiandrew antibioticsandinnateimmunityacooperativeefforttowardthesuccessfultreatmentofinfections AT rosewarren antibioticsandinnateimmunityacooperativeefforttowardthesuccessfultreatmentofinfections AT nizetvictor antibioticsandinnateimmunityacooperativeefforttowardthesuccessfultreatmentofinfections AT sakoulasgeorge antibioticsandinnateimmunityacooperativeefforttowardthesuccessfultreatmentofinfections |