Cargando…

A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation

Long noncoding RNAs (lncRNAs) are a heterogenous group of RNAs, which can encode small proteins. The extent to which developmentally regulated lncRNAs are translated and whether the produced microproteins are relevant for human development is unknown. Using a human embryonic stem cell (hESC)-based p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gaertner, Bjoern, van Heesch, Sebastiaan, Schneider-Lunitz, Valentin, Schulz, Jana Felicitas, Witte, Franziska, Blachut, Susanne, Nguyen, Steven, Wong, Regina, Matta, Ileana, Hübner, Norbert, Sander, Maike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423336/ https://www.ncbi.nlm.nih.gov/pubmed/32744504 http://dx.doi.org/10.7554/eLife.58659

Ejemplares similares

Fucoidan Inhibits the Progression of Hepatocellular Carcinoma via Causing lncRNA LINC00261 Overexpression
por: Ma, Danhui, et al.
Publicado: (2021)

LINC00261: a burgeoning long noncoding RNA related to cancer
por: Zhang, Menggang, et al.
Publicado: (2021)

Multifunctional RNA-binding proteins influence mRNA abundance and translational efficiency of distinct sets of target genes
por: Schneider-Lunitz, Valentin, et al.
Publicado: (2021)

A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion
por: Witte, Franziska, et al.
Publicado: (2021)

The lncRNAs LINC00261 and LINC00665 are upregulated in long-term prostate cancer adaptation after radiotherapy
por: Eke, Iris, et al.
Publicado: (2021)

Long non-coding RNA LCAL62 / LINC00261 is associated with lung adenocarcinoma prognosis
por: Dang, Ha X., et al.
Publicado: (2020)

LncRNA LINC00261 overexpression suppresses the growth and metastasis of lung cancer via regulating miR-1269a/FOXO1 axis
por: Guo, Caixia, et al.
Publicado: (2020)

Long non-coding RNA LINC00261 sensitizes human colon cancer cells to cisplatin therapy
por: Wang, Z.K., et al.
Publicado: (2017)

LINC00261 Is Differentially Expressed in Pancreatic Cancer Subtypes and Regulates a Pro-Epithelial Cell Identity
por: Dorn, Agnes, et al.
Publicado: (2020)

Methylation-mediated LINC00261 suppresses pancreatic cancer progression by epigenetically inhibiting c-Myc transcription
por: Liu, Songsong, et al.
Publicado: (2020)

LINC00261 and the Adjacent Gene FOXA2 Are Epithelial Markers and Are Suppressed during Lung Cancer Tumorigenesis and Progression
por: Dhamija, Sonam, et al.
Publicado: (2018)

Long non‐coding RNA linc00261 suppresses gastric cancer progression via promoting Slug degradation
por: Yu, Yingcong, et al.
Publicado: (2016)

Long non-coding RNA Linc00261 as a novel potential diagnostic and prognostic biomarker for gallbladder cancer
por: Niu, Jia-Zeng, et al.
Publicado: (2020)

Long Noncoding RNA LINC00261 Suppresses Cell Proliferation and Invasion and Promotes Cell Apoptosis in Human Choriocarcinoma
por: Wang, Yinan, et al.
Publicado: (2017)

Long noncoding RNA LINC00261 upregulates ITIH5 to impair tumorigenic ability of pancreatic cancer stem cells
por: Zou, Lijuan, et al.
Publicado: (2021)

Long noncoding RNA LINC00261 suppresses prostate cancer tumorigenesis through upregulation of GATA6-mediated DKK3
por: Li, Yang, et al.
Publicado: (2020)

Long Noncoding RNA LINC00261 Reduces Proliferation and Migration of Breast Cancer Cells via the NME1-EMT Pathway
por: Guo, Guangxiu, et al.
Publicado: (2020)

LINC00261 Inhibits Esophageal Cancer Radioresistance by Down-Regulating microRNA-552-3p and Promoting DIRAS1
por: Yang, Baolong, et al.
Publicado: (2021)

Linc00261 Inhibited High-Grade Serous Ovarian Cancer Progression through miR-552-ATG10-EMT Axis
por: Wang, Lin, et al.
Publicado: (2022)

LINC00261 Inhibits Esophageal Cancer Radioresistance by Down-Regulating microRNA-552-3p and Promoting DIRAS1 [Retraction]
Publicado: (2023)

Effects of LINC00261 targeting miR-148a/WNT10b axis on the proliferation and apoptosis of colorectal cancer cells
por: Xi, Juanli, et al.
Publicado: (2023)

A 3-dimensional human embryonic stem cell (hESC)-derived model to detect developmental neurotoxicity of nanoparticles
por: Hoelting, Lisa, et al.
Publicado: (2012)

LINC00261 elevation inhibits angiogenesis and cell cycle progression of pancreatic cancer cells by upregulating SCP2 via targeting FOXP3
por: Zou, Jun, et al.
Publicado: (2021)

TGF-β1 induced deficiency of linc00261 promotes epithelial–mesenchymal-transition and stemness of hepatocellular carcinoma via modulating SMAD3
por: Chen, Zhanjun, et al.
Publicado: (2022)

The LINC00261/MiR105-5p/SELL axis is involved in dysfunction of B cell and is associated with overall survival in hepatocellular carcinoma
por: Song, Hao, et al.
Publicado: (2022)

Epigenetic silencing of LncRNA LINC00261 promotes c-myc-mediated aerobic glycolysis by regulating miR-222-3p/HIPK2/ERK axis and sequestering IGF2BP1
por: Zhai, Shuyu, et al.
Publicado: (2020)

Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR-552-5p/FOXO3 axis
por: Chen, Tengxiang, et al.
Publicado: (2020)

LINC00261 Suppresses Cisplatin Resistance of Esophageal Squamous Cell Carcinoma Through miR-545-3p/MT1M Axis
por: Wang, Lijun, et al.
Publicado: (2021)

The evolutionarily conserved long non‐coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms
por: Mather, Rebecca L., et al.
Publicado: (2021)

Integrative analysis of macrophage ribo-Seq and RNA-Seq data define glucocorticoid receptor regulated inflammatory response genes into distinct regulatory classes
por: Ansari, Suhail A., et al.
Publicado: (2022)

Decreased expression of the long noncoding RNA LINC00261 indicate poor prognosis in gastric cancer and suppress gastric cancer metastasis by affecting the epithelial–mesenchymal transition
por: Fan, Yu, et al.
Publicado: (2016)

A Network of microRNAs Acts to Promote Cell Cycle Exit and Differentiation of Human Pancreatic Endocrine Cells
por: Jin, Wen, et al.
Publicado: (2019)

Impact of endocrine disruptors on peripheral blood mononuclear cells in vitro: role of gender
por: Maddalon, Ambra, et al.
Publicado: (2023)

Retraction Note to: Decreased expression of the long noncoding RNA LINC00261 indicate poor prognosis in gastric cancer and suppress gastric cancer metastasis by affecting the epithelial–mesenchymal transition
por: Fan, Yu, et al.
Publicado: (2018)

Sarcopenia in Endocrine Disorders – The Iceberg or Its Tip?
por: Minetto, Marco A, et al.
Publicado: (2015)

N (6)-Methyladenosine modification of lincRNA 1281 is critically required for mESC differentiation potential
por: Yang, Dandan, et al.
Publicado: (2018)

Downregulation of Long Noncoding RNA LINC00261 Attenuates Myocardial Infarction through the miR-522-3p/Trinucleotide Repeat-Containing Gene 6a (TNRC6A) Axis
por: Jiang, Chaoxin, et al.
Publicado: (2021)

FOXO3a‐mediated long non‐coding RNA LINC00261 resists cardiomyocyte hypoxia/reoxygenation injury via targeting miR23b‐3p/NRF2 axis
por: Zhang, Ruining, et al.
Publicado: (2020)

The potency of lncRNA MALAT1/miR-155/CTLA4 axis in altering Th1/Th2 balance of asthma
por: Liang, Zhijun, et al.
Publicado: (2020)

Analysis of lncRNA sequences: FAM3D-AS1, LINC01230, LINC01315 and LINC01468 in endometrial cancer
por: Bieńkiewicz, Jan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0arcj3r98u3uji5fcaqooemqln