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Protective Effects of Leukadherin1 in a Rat Model of Targeted Experimental Autoimmune Encephalomyelitis (EAE): Possible Role of P47phox and MDA Downregulation

BACKGROUND: Reactive oxygen and nitrogen species (ROS and RNS) are involved in pathologic mechanisms underlying demyelination and exacerbation in multiple sclerosis (MS) lesions. P47phox is the most important subunit of an ROS-producing enzyme (NADPH oxidase) which is reportedly upregulated in MS pl...

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Detalles Bibliográficos
Autores principales:	Hemmati, Sara, Sadeghi, Mohammad Amin, Yousefi-Manesh, Hasan, Eslamiyeh, Mostafa, Vafaei, Ali, Foroutani, Laleh, Donyadideh, Ghazaleh, Dehpour, AhmadReza, Rezaei, Nima
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423460/ https://www.ncbi.nlm.nih.gov/pubmed/32821147 http://dx.doi.org/10.2147/JIR.S258991

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