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Non-Conforming Still’s Disease With Low Ferritin and No Skin Rash: A Case Report

Adult Still's disease (ASD) is an inflammatory disorder with an unclear etiology. It is a rare disease that was first described more than a century ago. Its common characteristics are daily fevers, arthritis, and skin rash. ASD is diagnosed after excluding infections, malignancies, and connecti...

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Autores principales: Khan, Dawlat, Saddique, Muhammad Umar, Jamshaid, Muhammad B, Yousaf, Zohaib, Yassin, Mohamed A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423497/
https://www.ncbi.nlm.nih.gov/pubmed/32802605
http://dx.doi.org/10.7759/cureus.9168
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author Khan, Dawlat
Saddique, Muhammad Umar
Jamshaid, Muhammad B
Yousaf, Zohaib
Yassin, Mohamed A
author_facet Khan, Dawlat
Saddique, Muhammad Umar
Jamshaid, Muhammad B
Yousaf, Zohaib
Yassin, Mohamed A
author_sort Khan, Dawlat
collection PubMed
description Adult Still's disease (ASD) is an inflammatory disorder with an unclear etiology. It is a rare disease that was first described more than a century ago. Its common characteristics are daily fevers, arthritis, and skin rash. ASD is diagnosed after excluding infections, malignancies, and connective tissue diseases. It has a female predominance. Classic skin rash and high serum ferritin levels are commonly associated with this condition and help in the diagnosis. Due to a lack of pathognomic clinical and laboratory features, a valid diagnostic criterion, the Yamaguchi criteria, is generally used for the diagnosis. The disease has a good prognosis with appropriate treatment. We present the case of a young gentleman who presented with fever, anemia, and leucocytosis; however, his serum ferritin levels were normal, and there was no typical salmon-colored skin rash. Hyperferritinemia developed later in the disease course, leading to a diagnosis of ASD.
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spelling pubmed-74234972020-08-14 Non-Conforming Still’s Disease With Low Ferritin and No Skin Rash: A Case Report Khan, Dawlat Saddique, Muhammad Umar Jamshaid, Muhammad B Yousaf, Zohaib Yassin, Mohamed A Cureus Internal Medicine Adult Still's disease (ASD) is an inflammatory disorder with an unclear etiology. It is a rare disease that was first described more than a century ago. Its common characteristics are daily fevers, arthritis, and skin rash. ASD is diagnosed after excluding infections, malignancies, and connective tissue diseases. It has a female predominance. Classic skin rash and high serum ferritin levels are commonly associated with this condition and help in the diagnosis. Due to a lack of pathognomic clinical and laboratory features, a valid diagnostic criterion, the Yamaguchi criteria, is generally used for the diagnosis. The disease has a good prognosis with appropriate treatment. We present the case of a young gentleman who presented with fever, anemia, and leucocytosis; however, his serum ferritin levels were normal, and there was no typical salmon-colored skin rash. Hyperferritinemia developed later in the disease course, leading to a diagnosis of ASD. Cureus 2020-07-13 /pmc/articles/PMC7423497/ /pubmed/32802605 http://dx.doi.org/10.7759/cureus.9168 Text en Copyright © 2020, Khan et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Khan, Dawlat
Saddique, Muhammad Umar
Jamshaid, Muhammad B
Yousaf, Zohaib
Yassin, Mohamed A
Non-Conforming Still’s Disease With Low Ferritin and No Skin Rash: A Case Report
title Non-Conforming Still’s Disease With Low Ferritin and No Skin Rash: A Case Report
title_full Non-Conforming Still’s Disease With Low Ferritin and No Skin Rash: A Case Report
title_fullStr Non-Conforming Still’s Disease With Low Ferritin and No Skin Rash: A Case Report
title_full_unstemmed Non-Conforming Still’s Disease With Low Ferritin and No Skin Rash: A Case Report
title_short Non-Conforming Still’s Disease With Low Ferritin and No Skin Rash: A Case Report
title_sort non-conforming still’s disease with low ferritin and no skin rash: a case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423497/
https://www.ncbi.nlm.nih.gov/pubmed/32802605
http://dx.doi.org/10.7759/cureus.9168
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