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Cerebellar Predominant Increase in mRNA Expression Levels of Sirt1 and Sirt3 Isoforms in a Transgenic Mouse Model of Huntington’s Disease

The potential role of Sirt1 and Sirt2 subtypes of Sirtuins (class III NAD(+)-dependent deacetylases) in the pathogenesis of Huntington’s disease (HD) has been extensively studied yielding some controversial results. However, data regarding the involvement of Sirt3 and their variants in HD are consid...

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Detalles Bibliográficos
Autores principales:	Salamon, Andras, Maszlag-Török, Rita, Veres, Gábor, Boros, Fanni Annamária, Vágvölgyi-Sümegi, Evelin, Somogyi, Anett, Vécsei, László, Klivényi, Péter, Zádori, Dénes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2020
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423862/ https://www.ncbi.nlm.nih.gov/pubmed/32524313 http://dx.doi.org/10.1007/s11064-020-03069-0

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