XPO1 Gene Therapy Attenuates Cardiac Dysfunction in Rats with Chronic Induced Myocardial Infarction

Transcriptomic signature of XPO1 was highly expressed and inversely related to left ventricular function in ischemic cardiomyopathy patients. We hypothesized that treatment with AAV9-shXPO1 attenuates left ventricular dysfunction and remodeling in a myocardial infarction rat model. We induced myocar...

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Detalles Bibliográficos
Autores principales: García-Manzanares, María, Tarazón, Estefanía, Ortega, Ana, Gil-Cayuela, Carolina, Martínez-Dolz, Luis, González-Juanatey, José Ramón, Lago, Francisca, Portolés, Manuel, Roselló-Lletí, Esther, Rivera, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423868/
https://www.ncbi.nlm.nih.gov/pubmed/31768947
http://dx.doi.org/10.1007/s12265-019-09932-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423868/
https://www.ncbi.nlm.nih.gov/pubmed/31768947
http://dx.doi.org/10.1007/s12265-019-09932-y

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